Well they look like a solid team but clearly are beatable.
There C Alexander González (3110084) has been getting some very good ratings so that is something to consider when you choose their tactics. I probably would avoid low post and look inside. Your guy Simeón Cacho (11861462) is nice but I think Alexander wins this matchup.
The SF Erwin Obernöder (4587048) Small Forward looks good but has been getting much worse ratings, I suspect he has bad defence but is a rebound machine.
In their non-PL games they have been mostly playing look inside (22 from 26 times this season) and 3-2 zone (15 from 22 times) which suggests you may want to try something like a 2-3 zone yourself with a neutral offence like push the ball, patient or base so your team looks for the best shots given, seeing as their C puts you off inside offences and the 3-2 zone puts you off outside offences.
On the other hand in their last PL game they ran princeton and m2m the one before r&g and m2m, which could suggest you should play m2m and look inside.
Helpful or confusing, up to you.